Description du poste
About the Role In this project we are looking into the mechanisms that lead to production of autoantibodies in inflammatory and autoimmune diseases. We will be using Behçet’s disease and rheumatoid arthritis as disease models to investigate the interactions between B cells and Gamma Delta T cells. Key duties involve: Processing of patients’ blood samples; isolation of purified population of gamma delta T cells and B cells for co-culturing and RNA isolation; performing flow cytometry and biochemical experiments; conducting bioinformatics analyses. About You Qualifications in molecular biology, biochemistry, genetics or a related area. Desired good knowledge of immunology and experience in cell culture, cell sorting and flow cytometry techniques. About the School/Department/Institute/Project The Institute of Dentistry is part of the Faculty of Medicine and Dentistry at Queen Mary University of London (QMUL), a leading Russell Group university. It integrates research and teaching, combining a heritage dating back to 1911 and roots from St Bartholomew's and The London Hospital Medical College, with modern scientific inquiry. Our centre is located in The Blizard Institute, Whitechapel campus. Our research group investigates the phenotypic and functional characteristics of innate and adaptive immune cells in oral diseases and systemic inflammatory diseases with oral manifestations. The specific project aims to understand the interactions between gamma delta T cell and B cells in Behçet’s disease leading to autoantibody production. For this we use approaches including cell and molecular biology, in vitro cell functional assays, flow cytometry, immunological techniques and bioinformatics. About Queen Mary At Queen Mary University of London, we believe that a diversity of ideas helps us achieve the previously unthinkable. Throughout our history, we’ve fostered social justice and improved lives through academic excellence. And we continue to live and breathe this spirit today, not because it’s simply ‘the right thing to do’ but for what it helps us achieve and the intellectual brilliance it delivers. We continue to embrace diversity of thought and opinion in everything we do, in the belief that when views collide, disciplines interact, and perspectives intersect, truly original thought takes form. Benefits We offer competitive salaries, access to a generous pension scheme, 30 days’ leave per annum (pro-rata for part-time/fixed-term), a season ticket loan scheme and access to a comprehensive range of personal and professional development opportunities. In addition, we offer a range of work life balance and family friendly, inclusive employment policies, flexible working arrangements, and campus facilities. Queen Mary’s commitment to our diverse and inclusive community is embedded in our appointments processes. Reasonable adjustments will be made at each stage of the recruitment process for any candidate with a disability. We are open to considering applications from candidates wishing to work flexibly.